June 28, 2013
A team of researchers, fuelled predominantly by Western's Brain and Mind Institute, won top prize in the Hackathon at the annual meeting of the Organization for Human Brain Mapping last week in Washington.
Western, led by neuroscientist Rhodri Cusack - and a collaborator from Washington University, developed a novel approach to better understand how the human brain processes sounds.
The winning entry, titled No sound consensus, Cusack and his colleagues successfully mined terabytes (one terabyte equals one trillion bytes) of high-definition images showing connections in the brain from the Human Connectome Project. They then combined these samples with gene expression data from the Allen Brain Atlas to identify distinct parts of the brain's auditory cortex.
to Cusack, while there is consensus among scientists on how the visual cortex
should be parceled up, such a clear structure has never before been
demonstrated with the human auditory cortex.
"Moving forward, the structure we developed for the Hackathon will provide a framework for understanding how the human brain processes sounds, such as speech, music or environmental noises," said Cusack. "This, in turn, will help us understand how this system can become disrupted, in developmental disorders like dyslexia, following brain injury due to disturbances like aphasia or amusia or even psychiatric conditions like hallucinations."
Any single type of data is subject to biases, so three types were fused by this international and multidisciplinary team of scientists using a diverse range of analytical approaches, software packages and programming languages. The team estimates their entry used approximately one year's worth of processing time of the fastest processing cores in Amazon Web Services’ cloud and followed more than 3.6 billion connections through the brain.